Isaac

Offensive

• Quad shot + Explosive shot + Reusable fly generator
  • Optional: Quick charge

High DPS, flies have high damage. Most monsters killed by files, boss killed easily by attacks.

• Big shots + Max shot speed + Max shot damage

Quickly resolve anything.

• Flood shot + Antigravity + Magnetic tears

Creates a big shot ball, enemies are dragged into it and instantly killed. Even for bosses. Afterwards, the ball becomes a flood like normal flood attack.

Improvements

• PhD + Miner's hat

You can find many hidden rooms, and with PhD they have good pills. (Some hidden rooms contain many mushrooms, which contain pills)

Defensive

Offense is the best defense!

• 3 x Pretty files
  • Or replace one with meat cube

Breaks most projectiles